Monday, June 30, 2008

Tobira Therapeutics Inc. Announces Senior Management Team

- Senior management team possessing over 130 years of cumulative expertise
-

PRINCETON, N.J. and SAN DIEGO, June 30 /PRNewswire/ -- Tobira
Therapeutics Inc., a clinical stage biotechnology company committed to the
research and product discovery against life-threatening and life-altering
infectious diseases, today announced the organization of the company's
senior management team. Tobira Therapeutics has been led since its
inception in 2006 by James Sapirstein, RPh, MBA as Chief Executive Officer
and President. Joining James is Sandra Palleja, MD, Executive
Vice-President and Chief Medical Officer, Angeline Shashlo, RPh, Senior
Vice-President Regulatory Affairs and Quality Assurance, and Jay Rheingold,
PhD, Vice-President Chemistry Manufacturing and Controls. These additions
continue to build the management team with world-class pharmaceutical
development experts. "With this senior management team Tobira Therapeutics
has more than 130 years of combined pharmaceutical experience, with the
majority focused in biotech companies or HIV compounds. We are perfectly
positioned to bring novel molecules to market that will play an important
role in the treatment of HIV infection".

Dr. Palleja is the Chief Medical Officer, responsible for the overall
clinical development of the Tobira Therapeutics portfolio. Sandra joined
Tobira from Shionogi USA, where she lead numerous clinical programs as Vice
President of Clinical Development in several therapeutic categories
including an HIV joint venture with GSK. Prior to her years at Shionogi,
Sandra gained additional experience from both Triangle Pharmaceutics and
Hoffman-LaRoche, where she helped develop a variety of antivirals for HIV
and hepatitis including FTC, DAPD, ganciclovir, and saquinavir. Prior to
her career in industry, she was the Director of the Infectious Diseases
Clinic at St. Vincent's Hospital and Medical Center of New York City during
the mid to late 90's. Prior to her years at St. Vincent's, Sandra was an
Associate Professor of Medicine, served as the Primary Care Liason to the
AIDS Team at the Albert Einstein College of Medicine and Bronx Municipal
Hospital Center. From 1989-1993, she also served as Consultant to the AIDS
Institute, NYSDOH and the Federally Funded Ryan White Title III Program.
She earned her MD from Boston University School of Medicine.

Ms. Shashlo joined Tobira from Incyte Corporation where she held a
similar role as the VP of Regulatory Affairs and Quality Assurance. Prior
to Incyte, Angie spent several years working with start-up companies such
as Genaera, Vitagen and Ligand in a variety of roles including Project
Management. Angeline spent many years working for larger pharmaceutical
companies such as Wyeth and Upjohn during the first half of her 25-year
career in positions of increasing responsibility. Angie received her
Bachelor of Science in Pharmacy from the University of Michigan.

Dr. Rheingold brings over 29 years of experience in new product
scale-up, formulation development and manufacturing to Tobira Therapeutics.
Jay has successfully brought over 25 products to market during his tenure
at Lederle, Hoffman-LaRoche, Bristol-Myers Squibb and Organon
pharmaceutical companies. He received his doctorate in Pharmaceutical
Sciences from the University of Connecticut. Jay joins Tobira from Barrier
Therapeutics, where he held the position of Vice-President.

About Tobira Therapeutics, Inc.

Tobira Therapeutics is a private biopharmaceutical company which is
focused on developing and commercializing innovative antiviral compounds to
treat HIV disease. The company was founded in 2006 by Eckard Weber, MD, a
partner at the venture capital firm Domain Associates, to develop novel
treatments for HIV disease. Tobira has assembled a highly experienced
management team with decades of clinical and commercial development
experience specifically in HIV/AIDS drug development.



Contact:
Tobira Therapeutics Inc.
James Sapirstein CEO and President Tobira Therapeutics, Inc.
jsapirstein@tobiratherapeutics.com
Tel: 609-897-1102
http://www.tobiratherapeutics.com


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